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Masaomi Nangaku Selected Research

Biomarkers (Surrogate Marker)

10/2023eGFR slope as a surrogate endpoint for end-stage kidney disease in patients with diabetes and eGFR > 30 mL/min/1.73 m2 in the J-DREAMS cohort.
10/2023Application of urinary biomarkers for diagnosing acute kidney injury in critically ill patients without baseline renal function data.
10/2023eGFR slope as a surrogate endpoint for clinical study in early stage of chronic kidney disease: from The Japan Chronic Kidney Disease Database.
1/2023Rationale and design of an investigator-initiated, multicenter, prospective, placebo-controlled, double-blind, randomized trial to evaluate the effects of finerenone on vascular stiffness and cardiorenal biomarkers in type 2 diabetes and chronic kidney disease (FIVE-STAR).
10/2022Snapshots of nascent RNA can validate different nephron segment responses in acute kidney injury: a step toward clinically useful biomarkers?
1/2022Potential progression biomarkers of diabetic kidney disease determined using comprehensive machine learning analysis of non-targeted metabolomics.
1/2022Analysis of inflammatory cytokines and estimated glomerular filtration rate decline in Japanese patients with diabetic kidney disease: a pilot study.
1/2021The Future of Nephrology and Public Health.
7/2020Different Biomarker Kinetics in Critically Ill Patients with High Lactate Levels.
4/2018Importance of glomerular filtration rate change as surrogate endpoint for the future incidence of end-stage renal disease in general Japanese population: community-based cohort study.
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Masaomi Nangaku Research Topics

Disease

113Hypoxia (Hypoxemia)
03/2024 - 07/2003
94Chronic Renal Insufficiency
05/2024 - 05/2006
61Anemia
04/2024 - 01/2006
37Acute Kidney Injury (Acute Renal Failure)
04/2024 - 03/2004
35Diabetic Nephropathies (Diabetic Nephropathy)
05/2024 - 01/2002
34Proteinuria
10/2023 - 10/2001
30Type 2 Diabetes Mellitus (MODY)
05/2024 - 04/2008
30Neoplasms (Cancer)
12/2022 - 02/2008
27Fibrosis (Cirrhosis)
07/2023 - 04/2002
26Kidney Diseases (Kidney Disease)
04/2024 - 10/2008
21Albuminuria
04/2024 - 08/2011
21Inflammation (Inflammations)
09/2022 - 07/2006
19Chronic Kidney Failure (Chronic Renal Failure)
10/2023 - 01/2002
16Renal Insufficiency (Renal Failure)
04/2024 - 06/2004
16Reperfusion Injury
01/2023 - 03/2004
15Hypertension (High Blood Pressure)
01/2023 - 05/2003
13Body Weight (Weight, Body)
04/2024 - 12/2005
13Heart Failure
02/2024 - 10/2012
13Ischemia
01/2023 - 03/2004
12Atypical Hemolytic Uremic Syndrome
06/2023 - 01/2014
11Cardiovascular Diseases (Cardiovascular Disease)
02/2024 - 06/2006
11Infections
12/2021 - 02/2014
10Thrombotic Microangiopathies
06/2023 - 10/2001
10Diabetes Mellitus
01/2023 - 01/2015
9Glomerulonephritis
03/2024 - 01/2002
9Nephrotic Syndrome (Syndrome, Nephrotic)
12/2017 - 12/2004
7Sepsis (Septicemia)
07/2020 - 01/2014
6IGA Glomerulonephritis (IGA Nephropathy)
04/2024 - 01/2002
6COVID-19
12/2023 - 08/2020
6Disease Progression
12/2023 - 10/2018
6Hypophosphatemia
10/2023 - 01/2017
6Critical Illness (Critically Ill)
10/2023 - 01/2016
6Hyperglycemia
01/2021 - 12/2005
6Obesity
01/2020 - 12/2005
6Membranous Glomerulonephritis (Membranous Nephropathy)
02/2018 - 05/2005
6Nephritis
04/2015 - 01/2002
5Osteomalacia
12/2023 - 06/2019
5Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
01/2020 - 07/2012
5Thrombosis (Thrombus)
01/2020 - 10/2001

Drug/Important Bio-Agent (IBA)

32Prolyl-Hydroxylase InhibitorsIBA
03/2024 - 12/2007
27Oxygen (Dioxygen)IBA
01/2022 - 01/2004
26CreatinineIBA
04/2024 - 08/2011
26Proteins (Proteins, Gene)FDA Link
01/2023 - 01/2002
22Hemoglobins (Hemoglobin)IBA
03/2024 - 07/2006
22Glucose (Dextrose)FDA LinkGeneric
02/2024 - 05/2003
22ErythropoietinFDA Link
01/2024 - 01/2006
21HematinicsIBA
03/2024 - 08/2013
19Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
01/2024 - 01/2006
17Complement System Proteins (Complement)IBA
06/2023 - 01/2002
16Biomarkers (Surrogate Marker)IBA
10/2023 - 01/2014
14AlbuminsIBA
04/2024 - 03/2008
13SodiumIBA
02/2024 - 09/2011
13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 12/2004
12enarodustatIBA
04/2022 - 01/2019
11empagliflozinIBA
04/2024 - 05/2019
11IronIBA
11/2023 - 12/2005
11Darbepoetin alfa (Aranesp)FDA Link
09/2023 - 01/2015
11Transcription Factors (Transcription Factor)IBA
02/2021 - 11/2005
9Blood Glucose (Blood Sugar)IBA
04/2024 - 08/2011
9Advanced Glycation End ProductsIBA
09/2022 - 10/2002
9Messenger RNA (mRNA)IBA
01/2019 - 04/2004
8Sodium-Glucose Transporter 2 InhibitorsIBA
04/2024 - 01/2019
8Histones (Histone)IBA
01/2023 - 01/2011
8RNA (Ribonucleic Acid)IBA
10/2022 - 01/2002
7CytokinesIBA
01/2023 - 01/2011
7GSK1278863IBA
12/2022 - 01/2017
7ElementsIBA
11/2022 - 12/2004
7EnzymesIBA
10/2019 - 02/2008
6vadadustatIBA
03/2024 - 07/2020
6bardoxolone methylIBA
11/2023 - 10/2019
6Phosphates (Orthophosphate)IBA
10/2023 - 01/2017
6SteroidsIBA
09/2023 - 10/2014
6cobaltous chloride (cobalt(II)chloride)IBA
01/2023 - 11/2011
6Fibroblast Growth Factor-23IBA
12/2022 - 01/2017
6Insulin (Novolin)FDA Link
12/2022 - 05/2003
6Antihypertensive Agents (Antihypertensives)IBA
07/2022 - 05/2003
6Dipeptidyl-Peptidase IV InhibitorsIBA
05/2022 - 09/2011
6Lipocalin-2IBA
08/2020 - 11/2013
6DNA (Deoxyribonucleic Acid)IBA
01/2020 - 05/2013
6CobaltIBA
01/2018 - 07/2003
5Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
10/2023 - 07/2015
5Uremic ToxinsIBA
01/2023 - 08/2010
5esaxerenoneIBA
01/2023 - 01/2019
5CalciumIBA
12/2022 - 05/2014
5PotassiumIBA
11/2022 - 04/2017
5Small Interfering RNA (siRNA)IBA
12/2020 - 08/2015
5eculizumabFDA Link
04/2019 - 07/2016
5Angiotensin IIIBA
01/2015 - 02/2004
4Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
04/2024 - 05/2003
4Adrenocorticotropic Hormone (ACTH)FDA Link
10/2023 - 01/2015
4AntibodiesIBA
06/2023 - 12/2017

Therapy/Procedure

56Therapeutics
04/2024 - 04/2003
25Renal Dialysis (Hemodialysis)
03/2024 - 04/2003
11Peritoneal Dialysis
04/2024 - 09/2005
10Renal Replacement Therapy (Therapies, Renal Replacement)
04/2024 - 01/2019
7Kidney Transplantation
04/2024 - 03/2004
6Continuous Renal Replacement Therapy
10/2023 - 04/2015
6Plasma Exchange
04/2019 - 07/2006
5Catheters
12/2021 - 10/2020
4Glycemic Control
02/2024 - 01/2010